reMYND

NV reMYND is a biotech spin-off of the University of Leuven (Belgium).

reMYND is active in the field of Alzheimer’s disease and Parkinson’s disease. In 2004 reMYND received the Flanders' Most Innovative Start-up Award. The company consists of 2 units :

• Service Unit
  • CRO mainly focused on Alzheimer transgenic mouse models with amyloid pathology.
  • In vitro genotoxicity testing & licensing of RadarScreen
• Drug Discovery Unit focused on tau (as target for Alzheimer's disease) and α-synuclein (as target for Parkinson's disease).

Gaston Geenslaan 1
B-3001 Leuven (Heverlee)
Belgium
T +32 16 75 14 20
F +32 16 75 14 21
reMYND@remynd.be





NV reMYND, a company spinned-out from Leuven University in 2002, has devoted the first years of its existence to develop a technology platform suited for high-throughput drug identification. This platform consists of different high–throughput screens based on yeast cells expressing a known target. The screens exploit intrinsic properties of the human target protein and link these to a straightforward read-out: growth of the yeast culture.
Whereas the platform can be adapted to target virtually every protein-misfolding associated disease (e.g. Huntington, ALS, Creutzfeld-Jacob^nv), reMYND has focused on Alzheimer’s disease (using tau as target) and Parkinson’s disease (using α-synuclein as target. Competition on these highly relevant targets is limited, whereas both are key players in the etiology of respectively Alzheimer’s and Parkinson’s.
The yeast-based approach has been further complemented by model systems based on human cell lines (neuroblastoma) and animal models.
Within three years time we settled a productive drug candidate discovery engine addressing these two major diseases with unmet medical needs, and screened more than 25.000 novel molecules. This resulted in 6 currently active drug discovery programs, one of which has already delivered a candidate for entering the clinical development phases.
reMYND’s business development has been fueled by governmental grants and by income acquired through contract research.

Integrated DNA Technologies (IDT)

The Source for Custom DNA Synthesis A non-technical explanation of what IDT does can be found here IDT News and Press Releases IDT's Commitment to Quality Assurance and ISO 9001:2000 Certification IDT's ISO 13485:2003 Certification Careers at IDT Since 1987, Integrated DNA Technologies (IDT) has been a major force in advancing biotechnology research both as a leading supplier of custom oligonucleotides and a developer of innovative new biotechnologies. Researchers select IDT as their custom oligonucleotide supplier of choice for quality, service and price. Over 77,000 customers worldwide trust IDT for dependable products of the highest quality. In 2001, IDT dramatically expanded its manufacturing capacity and further enhanced its high-throughput synthesis division. IDT now routinely fulfills large-volume orders consisting of hundreds of thousands of oligonucleotides, while still maintaining quality controls that are second to none. Today, every oligo synthesized is tested by mass spectrometry and must pass strict quality control guidelines to be shipped to the customer. In addition to improving the quality of custom synthesized DNA, IDT has dramatically shortened turnaround times by offering a variety of expedited services, such as SameDay® oligo synthesis, Rapid HPLCTM purification services, HOTplatesTM and Express DLPTM products. In addition to DNA, IDT has led the effort over the last decade to reduce the cost of high-quality custom RNA synthesis. Through improvements to the traditional tBDMS chemistry and advances in instrumentation, IDT has achieved the highest coupling efficiency in the industry. Only at IDT are customers guaranteed the very best in quality synthesis with free mass spectrometry and CE traces on all purified RNA oligos. In 2005, IDT's manufacturing headquarters achieved ISO 9001:2000 certification. IDT's success in achieving certification reflects the strength of its existing product quality procedures, as well as its clear commitment to the manufacturing excellence and the ongoing development of its quality management system. It also signifies the continuing commitment of IDT's management to strengthen the company's ability to identify and meet the needs and evolving expectations of its customers. Also in 2005, IDT acquired oligonucleotide provider Genbase and began manufacturing at its West Coast operations facility. IDT now accepts orders until 11p.m. ET. With more capacity and extended business hours, IDT provides the fastest, most reliable service worldwide. In early 2006, IDT completed a large expansion of its manufacturing headquarters facility. With 77,000 square feet added to IDT's already state-of-the-art facility (bringing the total square footage to 134,000) no oligonucleotide supplier is better equipped to fulfill the requests of researchers. From oligos in plates to Dicer-substrate RNAi duplexes in TriFECTaTM kits, IDT offers the best quality, customer service and turnaround time. In late 2006, IDT acquired the Leuven, Belgium company RNA-TEC. The strategic European acquisition of RNA-TEC (Integrated DNA Technologies, BVBA) bolstered IDT's product offerings in large-scale RNA synthesis and purification, particularly in the Dicer-substrate RNAi (DsiRNA) field and focusing on large-scale DsiRNA for compounds for large screens and animal studies. IDT, BVBA is also proficient in ribozyme and DNA/RNA aptamer products, as well as standard DNA small-scale offerings.

Innovation, Ongoing Research and Development In line with IDT's mission to advance research in DNA-based technologies, the research staff at IDT combines expertise in synthetic chemistry, biophysics, molecular biology, bioinformatics and engineering. IDT specializes in the areas of gene silencing based on RNAi, ddRNAi and antisense technologies, transcription profiling, DNA sequencing and SNP detection, microarray analysis and DNA amplification. This expertise has led to research and development collaborations with many leading biotechnology companies and academic laboratories. IDT's Commitment IDT continuously strives to bring customers the best in oligonucleotide synthesis, quality control and customer service. The staff and scientists at IDT are dedicated to insure the satisfaction of customers by providing many convenient benefits.

IDT's Quality Policy Products released to market will be of the highest quality, produced on time, and supported by professional customer service.

European Operations

Integrated DNA Technologies, BVBA
Interleuvenlaan 12A
B-3001 Leuven
BELGIUM

IRIS Biotech

IRIS Biotech is specialized in reagents for Peptide Ssynthesis and products for Life Science Research. We have specific know-how and production capabilities to manufacture and supply products from the following areas from Grams to Multi-Ton Lots:

	Starting Materials for Peptide Synthesis (Protected Amino Acids, Coupling Reagents, Linkers and Resins)
	Reagents for PEGylation (monodisperse and polydisperse; short (MW 300) to very long (MW 20.000) Glycol Spacers, hydrophobic and amphiphilic SpacerMolecules; Contract Manufacturing of PEG Spacers and PEGylation
	Reagents for Life Science Research (Aflatoxines, Cyclosporines, Cytochalasins, Geldanamycin, Methoxatin, Rapamycin, etc.)
	Carbohydrates (Derivatives of Arabinose, Galactose, Glucose, Mannose, Xylose, etc.)
	We are carrying out many Contract Manufacturing projects in these areas; our strong points are unusual derivatives with one or several chiral centres. We follow cGMP and ISO9000 and supply from typical lab scale for R&D to multi-ton bulk quantities for production, in order to escort our customers' projects during their evolution from R&D projects to commercial production.

Our Customers are from universities, research organisations, spin-off companies as well as pilot and production departments in world-wide operating concerns.

Our Mission is to escort our customers during their projects from R&D to Production as highly qualified supplier. We deliver lab quantities to research units for very competitive prices and supply increasing quantities with same quality and specifications during the evolution of our customers' products to pilot scale and even multi-ton commercial productions with bulk quantities.

Our Production Sites are our Joint-Venture partners:

	Siddhi Vinayaka Spechem P Ltd, Bangalore, India (ISO 9000, GMP certified),
	GIHON-Laboratorios Químicos SRL, in Mar del Plata, Argentina.
	Beside that we are cooperating on an exclusive basis with around 35 worldwide selected manufacturers and leading universities with specific expertise in the areas of our activities.

Maxi Cleaning

Maxi Cleaning maakt zijn naam helemaal waar. Iedere dag opnieuw.

Onze ervaren medewerkers kunnen zowel omvangrijke als kleinschalige opdrachten de baas. Hun doorgedreven opleiding en ons voortdurend uitgebreid en aangepast materiaal- en vrachtwagenpark staan daarvoor garant.

Maxi Cleaning is erkend ophaler van gevaarlijke en niet-gevaarlijke afvalstoffen. We beschikken over de vereiste vergunningen voor zowel Vlaanderen, Brussel als Wallonië. Dankzij ons VCA*-certificaat hebt u de zekerheid dat we alle veiligheidsvoorschriften naleven en aan de voorwaarden op het vlak van gezondheid en milieu voldoen.

Sinds onze start in 1983 hebben we een trouw en alsmaar groeiend cliënteel in de particuliere, industriële, openbare en overheidssector opgebouwd. Hoort u daar binnenkort ook bij? Op deze website vindt u een online offerteaanvraagformulier. Geheel vrijblijvend.

Maakt u graag eerst een afspraak om kennis te maken? Of hebt u een vervelend probleem dat om een dringende oplossing vraagt? Contacteer ons:

• per telefoon op het nummer 02 416 80 40
• per fax op het nummer 02 720 38 46
• per e-mail naar info@maxicleaning.be

Maxi Cleaning werd opgericht in 1983. Sindsdien zijn we van een regionaal opererende zaak met een beperkt aantal activiteiten uitgegroeid tot een volwaardige KMO die op nationaal vlak een waaier van ruimings- en aanverwante diensten aanbiedt. Ons cliënteel bestaat uit zowel particulieren en KMO’s als multinationals, openbare besturen en overheidsinstellingen. Vele onder hen rekenen sinds de prille beginjaren op onze diensten.